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Found on macrophages and neutrophils, particularly MC-1R and MC-3R constitute these sites when KPV bonds to these receptors, it arrests the production and release of pro-inflammatory cytokines TNF-, IL-1 and IL-6

This consistency in safety across different dosages and durations of administration highlights the peptides potential as a safe therapeutic agent

Both peptides show published activity across rodent and cell-culture tissue-repair models without binding a single canonical receptor, distinguishing the blend from receptor-targeted compounds