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M.MatsuokaK.et al (2011)
Molecules administered by intrathecal administration still encounter barriers within the subarachnoid space for drug penetration from CSF into brain parenchyma, but IT dosing creates a favorable concentration gradient for drugs to diffuse

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as the control mice group, experimental and treatment groups

[DOI] [PubMed] [Google Scholar] Wang J

Cornelis, F
