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Self-administration is a well-established animal model based on the principle of operant conditioning, in which an animal performs a specific behavior (e.g., pressing a lever) and is rewarded with a drug

2011 Jun;42(3):367-75

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

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This dysfunction occurs at the central level, involving the brain, and the peripheral level, involving non-spinal nerves throughout the body, and may be aggravated by crosstalk between the nervous system and immune cells