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These elements (e.g., cobalt, Co, copper, Cu, iron, Fe, manganese, Mn, molybdenum, Mo, or zinc, Zn) are essential for many basic physiological functions of organisms, such as oxygen transport, enzymatic reactions, and the maintenance of antioxidant defence mechanisms (Aliko et al., 2018

In some cells, it has been found in the peroxisomal compartment

Inflammation in cystic fibrosis lung disease: pathogenesis and therapy

J Nucl Med 2020 Mar;61(3):357-366 66

Treatment with nizatidine in combination with either vitamin E, thioctic acid or a combination of both resulted in a significant increase in erythrocytic GPx and SOD activities and a significant decrease in plasma MDA level

Improvements in several glycemic markers, including insulin levels and insulin resistance (IR), which are critical for managing NAFLD, have been shown in clinical studies (125, 129)