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For instance, lactate induces TGF-2 expression in glioma cells and knockdown of lactate dehydrogenase A (LDHA), an enzyme that catalyzes lactate production, downregulates TGF-2 levels ( TABLE 2 Modulation of TGF- signaling by metabolic changes
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The following polyclonal antibodies were used for immunoblotting: anti-MYO6 (rabbit
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