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Dere et al., reported that 43.2% of AHR-enriched genomic regions identified by genome-wide ChIP-chip analysis co-localize with a pDRE after 2 h of TCDD treatment when integrated with microarray differential gene expression data 62

Recent research has found a bidirectional interaction between the nervous system and immune system, signifying that systemic inflammation could cause selective neuronal activation (Brea and Veiga-Fernandes, 2022)

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L-Dopa Increases -synuclein DNA Methylation in Parkinson's Disease Patients In Vivo and In Vitro

First, the representation of the CNS microenvironment in existing models is insufficient

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