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Figure 1 ) reversed a number of age-related changes in liver mitochondrial function yet increased liver mitochondrial oxidant production (18)

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Intake of L-carnitine supplements has been shown to be an efficient therapeutic approach to treat disorders caused by L-carnitine deficiencies

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According to studies, hypertension may cause the gut-blood barrier to become more permeable, allowing more TMA to enter the bloodstream and raising the quantity of TMAO [55]

High TMAO levels in CKD patients have been associated with increased mortality and adverse cardiovascular outcomes, suggesting that TMAO could be a critical factor in the progression of CKD and its complications [72,73]