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These results strongly suggest that fumarate-induced oxidative stress is sufficient for the induction of p21 and the initiation of cell senescence, regardless of cells genotype
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Am J Trop Med Hygiene (1997) 5:5114
These oxidized phosphatidylcholines contribute to ferroptosis by disturbing mitochondrial function and suppressing GPX4 activity, shown in cardiomyocytes during ischemia-reperfusion injury [54]
IAP is also secreted into the serum, where it remains biologically active
Role of tumor and host autophagy in cancer metabolism
