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We showed that levels of LOX-metabolites were significantly higher in the mammary gland and plasma of rats administered DHA orally than in untreated rats although the increase in the plasma level of 4-HDHA derived from 5-LOX activation was not significant

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In a WT p53 restorable mouse model of LUAD, the LSL- WT p53 allele in the mice is phenotypically identical to the knockout state of the allele, but the expression of WT p53 can be induced upon the removal of LSL by a CRE recombinase [151]

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