glutathione peroxidase liver detoxification A Literature Review of Therapy in Ameliorating Hepatic Dysfunction in Non-Alcoholic Fatty Disease Glutathione - an overview |
Description
Neurobiol Aging 126:7790

As in other amino acids with an asymmetric carbon atom, the L-isomers of Met, Hcy, and Cys are the biologically active forms

doi: 10.1038/sj.cdd.4401662

The reaction is elegantly simple: 2GSH+H2O2GPxGSSG+2H2O2GSH+H2O2GPxGSSG+2H2 Two molecules of reduced glutathione (GSH) donate electrons to neutralize one molecule of hydrogen peroxide, producing water and oxidized glutathione (GSSG)

Just two members of OATP family (OATP-1 y OATP-2) accept GSH as substrate, releasing it into the blood stream

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