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Given that the pathogenesis of antiretroviral toxic neuropathy is based on the disruption of mitochondrial energy supply one can assume that the clinical effect of ALCAR is dependent on its mitochondrial availability
Previous study that ARKO (androgen receptor knock out) mice were euphagic compared to the wild-type male controls, but also less dynamic and less oxygen consuming

doi: 10.2165/00007256-200434010-00005

J.SilljeH
Front Endocrinol (Lausanne) 2023;14:1085041
