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Description
Challenges in the therapy of NeuroHIV As ART alone is insufficient to fully suppress HIV-1 replication, including the transcription and translation of HIV-1 provirus in both T-cell reservoirs and non-CD4 T-cell reservoirs, there is a critical need to develop new brain-penetrating agents that can effectively target both CNS and peripheral immune cells to simultaneously silence HIV-1 and reduce the risk of neuroinflammation
[PubMed: 17846744] 890
Unregulated drugs are often inconsistently dosed and have been found to carry contaminants like formaldehyde

Serglycin (Srgn) overexpression predicts poor prognosis in hepatocellular carcinoma patients

10.7554/eLife.96743 9 ChangJ.XavierH
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