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World Journal of Gastroenterology, 23(48), 8465-8488

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The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease

328 Covalent conjugation of targeting ligands, and/or polymeric materials such as PEG chains, carboxymethyl cellulose, dextran could distinctively facilitate the transport of IONPs across the BBB
The readout for the phase 3 trial of Ziltivekimab is expected in June 2026 if it works, and if its safe, it could establish IL6 inhibition as a new standard of care for cardiovascular risk reduction in chronic kidney disease