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Experimental studies increasingly suggest that curcumin-piperine combinations may exert synergistic neuroprotective effects by simultaneously targeting oxidative stress, neuroinflammation, mitochondrial dysfunction, and protein aggregation pathways (Banji et al., 2013
10.1371/journal.pone.0009069 PLoS One
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Unpaired chains precipitate within red cell precursors, forming insoluble inclusions
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