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Left-Sided Congestive Heart Failure (LS-CHF) Mechanism : Pathophysiology : In left-sided CHF, the left ventricle fails to effectively pump blood out to the body, causing blood to back up into the left atrium and then into the lungs

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The discovery that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) toxicity leads to Parkinsons-like disease provided strong evidence that complex I within mitochondria may be a major source of superoxide that initiates the disease (1043)

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