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Vitamin B 1 deficiency causes overexpression of pro-inflammatory cytokines such as interleukin (IL)-1, IL-6, and tumor necrosis factor-alpha (TNF-) as well as increased expression of CD40 and CD40 ligand by microglial cells and astrocytes, which eventually leads to the death of neuron cells [18,19]

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10.1016/j.jtbi.2004.09.004 217

[DOI] [PMC free article] [PubMed] [Google Scholar] Middleton 1985 Middleton J, Wells W
