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The authors attribute the positive results to the increase in SOD in the mouse brain, relating this substance to the potential against OS [151]

The complete removal of intronic regions flanking the GAA repeats showed the most significant restoration of FXN expression, compared to elimination of only the GAA tract, offering a potential therapeutic strategy for FRDA

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Iron is needed for proper development of oligodendrocytes (the brain cells that produce myelin) (19), and the mineral is also a required cofactor for several enzymes that synthesize neurotransmitters (68)
[DOI] [PubMed] [Google Scholar] 23.Nakamura K

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