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Furthermore, the immunohistochemistry analysis evaluated the protective effects of the Au-PX-PLGA on dopaminergic neurons in the striatum and tyrosine hydroxylase, which is an essential enzyme in dopamine synthesis, served as the biomarker for dopaminergic neuron integrity

After treatment, a mean increase of 75.27 mmHg in the PFO was noticed in the HABIT group, which was numerically higher than that of 51.23 mmHg in the control group, but the difference was not statistically significant ( p = 0.113, Fig

Drug-induced liver toxicity and prevention by herbal antioxidants: an overview

Results revealed that a single 250 mg dose significantly increased nitrate and nitrite levels in both blood serum and saliva within 24 h compared to the placebo group

Ursini F, Maiorino M

Thus, the longer survival of patients with higher IGF-1 levels could be related to direct biological actions of IGF-1, to an overactivation of a protective GH-IGF-1 pathway or to altered IGF-1 levels in patients with a favorable metabolic status