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The herb is also effective at managing some of the most debilitating PMS symptoms such as cramps and anxiety due to its anti-inflammatory and antispasmodic properties

74 Dysfunctional telomeres arise from critically short telomeres, ultimately leading to replicative cellular senescence and chromosome instability: both hallmarks of aging

doi:10.1017/S1461145713001685 McCoy, Alene T et al

This can lead to changes in blood cell counts, such as: reduced number of red blood cells (anemia) low platelet counts (thrombocytopenia) Low blood cell counts can cause complications, such as easy bruising or bleeding, or fatigue
Administration to animals with vitamin E deficiency
This is not specific to B12 but reflects the sensitivity of the gastrointestinal tract in these conditions