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Description
The aggregation of the mutated HTT gene triggers neuronal cell death through the apoptotic pathway, which mainly results from mitochondrial dysfunction [166,169]one of the important mechanisms involved in the pathology of HD [2,23,170]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 111.Yin Z, et al
10.1074/jbc.M115.700534 26 BronteV.KasicT.GriG.GallanaK.BorsellinoG.MarigoI.et al
A general hypoxia-responsive molecular container for tumor-targeted therapy
With ageing, the spatial organization and functional integrity of this vasculature undergo significant decline
