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ROS-induced OS causes alterations in different organ systems, which are explained as follows: ROS-induced neurotoxicity causes modulation in the neurons such as permeabilization of the cellular membrane, a decrease in the excitability property of neuronal membrane and the activation of the KATP pump (Figure 3)

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Acknowledgments We would like to acknowledge the work of Ewa Wrotkowska who performed the biochemical tests and the work of Wiktoria Domin who prepared digital versions of the figures

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