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have developed a set of devices, called EXOtic devices, that enable efficient and customizable production of designer exosomes in engineered mammalian cells [115]
The conversion of vitamin B 6 to its active coenzyme form in tissues, pyridoxal 5'-phosphate (PLP), requires the FMN-dependent enzyme, pyridoxine 5'-phosphate oxidase (PPO) (7)
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Thus, mitochondrion-targeted antioxidants represent a rational therapeutic avenue [239]
High intensity interval training (HIIT) and a flavonoid-rich diet have been identified as synergistic interventions for natural enhancement of BDNF
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