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Nitric Oxide 68:7790 Acknowledgements We thank the Sao Paulo State Foundation for Research Support (FAPESP, Brazil) for financial support through grants #2013/18056-2 and #2016/02033-1 and #2016/01128-99

doi: 10.1016/j.yjmcc.2010.02.001

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Pamies D, Wiersma D, Katt ME et al (2022) Human organotypic brain model as a tool to study chemical-induced dopaminergic neuronal toxicity

Furthermore, intervention strategies based on the 'injury-repair balance' framework should enable precise modulation according to the features of each phase, thereby shifting from 'passive suppression' to 'active regulation'