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Talarmin H, Rescan C, Cariou S, Glaise D, Zanninelli G, Bilodeau M, Loyer P et al

Clinicians often prescribe NSAIDs, including aspirin, ibuprofen, and more recently, COX-2 inhibitor such as celecoxib, to relieve pain and inflammation in OA patients, but these drugs often cause various side effects, including skin infections, gastric ulcers, mood changes, depression, and osteoporosis [353]

Gene expression profiling reveals new protective roles for vitamin C in human skin cells

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PMCID: PMC4043255