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Use of such ligands will allow the specific delivery, or specifically enhanced delivery, of such targeted agents to the central nervous system (CNS) for the treatment of brain diseases
Decreased levels of glutathione after transient ischemia in the hippocampus were described previously (Higashi et al
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Int J Environ Res Public Health 3:323328 Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, Biswal S (2006) Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

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