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Thus, GPx-1-deficient neurons have enhanced cell death after exposure to Abeta, whereas ebselen or N-acetyl-L-cysteine treatment or overexpression of GPx-1 significantly attenuated Abeta-induced toxicity (200)

This surface charge modulation is also critical for cationic liposomes designed to adhere to negatively charged skin membranes

423 Furthermore, the study emphasized that neurons in specific brain regions, such as the hindbrain and hypothalamus, co-express GLP-1R along with 1-adrenergic and -opioid receptors, suggesting a localized mechanism within the CNS that could coordinate peripheral anti-inflammatory responses

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Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitors

doi: 10.1172/JCI37048