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This hypothesis is supported by the appearance of lesions of HFSR specifically in areas chronically exposed to friction and with preexisting hyperkeratosis.20 Recently, the existence of a genetic predisposition to develop sorafenib-induced HFSR has been described in patients with hepatocellular carcinoma.21 Dranitsaris et al.22 developed and validated a predictive model for the onset of HFSR in patients receiving treatment with sorafenib.23,24 The management of HFSR is summarized in Table 3

Like H 2 O 2 , PLOOH can also undergo the Fenton reaction, a series of reaction where PLOOH can be converted to lipid hydroxy radical (PLO) and lipid peroxyl radical (PLOO)

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Surgical excision with histology is the first-line treatment for all skin cancers

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Your doctor may want to find out the level of this protein in your blood to find how your pancreas is doing