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Cannabinoid receptor type 1 (CB1) stimulates the binding of orexigenic peptides and inhibits the attachment of anorexigenic proteins to hypothalamic neurons in mammals, increasing food intake

Previous studies on the effects of BPC-157 peptide have shown positive and rapid healing effects of various muscle injuries, characterized by fewer accompanying hematomas and swelling or absence of post-injury contractures

Statements Author contributions NA wrote the manuscript, FS contributed in section introduction of this manuscript, while MA reviewed and updated the manuscript

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Gastroenterology 128(4 Suppl 1):S121S127

While current studies highlight promising therapeutic avenues, future research should focus on validating long-term safety and efficacy through larger cohorts, while also examining the functional stability of transplanted cells, their integration with host neural circuits, and any potential off-target or neuroimmune effects to ensure clinical translatability