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In an earlier one-week, three-arm trial [178], an aqueous kava product from a specific cultivar (Palarasul) was manufactured by MediHerbPty Ltd

The optimal UA reduction was achieved with the mass ratio of PDA to Pt at 1:1, which is comparable to the efficacy observed at 1:0.5 (Figure S10b)

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Importantly, none of the available treatments address the underlying neurodegeneration, and disease progression continues unabated

Thereafter, several variants of this model have been reported using mice of different strains, different ages or micro-coils of smaller or larger diameters (375)

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