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XL184 and XL880 are orally available, non-selective inhibitors, with high binding affinity to both Met and VEGFR and to a lesser extent to other receptor tyrosine kinases such as PDGFR, Ret, Kit, Flt-3 and Tie-2 (Liu et al., 2010)

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However, the injections may exacerbate certain medical problems or cause serious health issues

Reduce inflammation

Attenuation of adipocyte triacylglycerol hydrolase activity decreases basal fatty acid efflux

Wang Z, Hu W, Lu C, Ma Z, Jiang S, Gu C, et al