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Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis

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(1) The peptide has also been suggested to play some role in DNA repair, lung protection, fibroblast reactivation, and possibly in suppressing proinflammatory and pro-aging molecules like NFB

10.1016/j.cub.2020.10.095 [DOI] [PubMed] [Google Scholar] Zhang X, Davidson EA, Mauzerall DL, Searchinger TD, Dumas P, Shen Y

Some mice infected with mcp1 -/- a survived even after 40 days

Its mechanism of action is thought to involve anti-inflammatory pathways, promotion of endothelial cell function, and modulation of fibrosis