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2004), but experimental proof that this occurs at significant rates in mammalian cells and gives rise to the same type of adducts with GSH or lysine as cis -2-butene-1,4-dial (BDA) is still lacking

The covalent binding of valproic acid and its hepatotoxic metabolite, 2-n-propyl-4-pentenoic acid, in rats and in isolated rat hepatocytes

Unlike memory T cell differentiation in acute immune responses, exhausted T cells in GBM fail to sustain long-term antitumor immunity due to persistent antigen exposure, metabolic stress, and an immunosuppressive TME

(2008) conducted a controlled experimental study on a variety of traditional prescriptions for cirrhosis and found that YCHD most significantly inhibited -SMA activation and regulated rat cirrhosis

Life Sciences ence 55 :163-167

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