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10.5114/reum.2022.120752 [DOI] [PMC free article] [PubMed] [Google Scholar] 209.Liu T, Li S, Ying S, Tang S, Ding Y, Li Y, et al

Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal dominant disorder characterized by mutations in the FH gene that result in altered activity of fumarate hydratase, which is involved in the tricarboxylic acid cycle

Magnesium helps with DNA & RNA synthesis

doi: 10.1016/j.micinf.2005.12.004 177 OlivaresNLenALpezYPuigACdizAFaleroGet al

Devoid of the multi-layered smooth muscle and elastic fibers characteristic of normal vessels, these abnormal vessels not only fail to effectively alleviate hypoxia but exacerbate tissue edema through increased vascular leakage