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doi: 10.1186/s40035-020-00221-2 245 GaoCJiangJTanYChenS

We wanted to make that pit as cold as possible for as long as possible

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Detection of antibodies towards the antimalarial amodiaquine and its quinone imine metabolite in man and the rat

In cancer, lactate, an energy source and metabolic by-product, can shuttle between glycolytic tumor cells and oxidative tumor cells, thereby promoting tumor occurrence and development ( In vivo , lactylation at H4K12la promotes expression of Hif1 and enhances endometrial glycolysis, and in turn forms an H4K12la-Hif1-glycolysis feedback loop to drive decidualization ( Notably, pyruvate dehydrogenase kinase 4 (PDK4) mRNA expression exhibits significant upregulation during in vitro decidualization

Samples were incubated at 37 C for 10 min, immediately placed on ice, and transferred to a 0.5-mL Amicon Ultra 10 KDa filter