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These are generally shortlived

Regelmigkeit ist wichtiger als Intensitt

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doi: 10.1038/ijo.2013.120

The condensation reaction can be carried out at room temperature, sometimes requiring reflux at a certain temperature

Other protoberberine alkaloids in FRP, such as palmatine, jatrorrhizine, and columbamine could also show a moderate binding affinity with core target proteins
