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566 A phase III clinical trial demonstrated that adjuvant ipilimumab (10 mg/kg) was not superior in efficacy to IFN-2b, but ipilimumab (3 mg/kg) significantly improved the OS with lower toxicity compared with high-dose IFN-2b

Paternal diet induces transgenerational epigenetic inheritance of DNA methylation signatures and phenotypes in sheep model

Akbari A, Mobini GR, Agah S, Morvaridzadeh M, Omidi A, Potter E, Fazelian S, Ardehali SH, Daneshzad E, Dehghani S

By synthesizing existing clinical evidence and outlining future research priorities, this section provides insights into how RCD-based strategies can be optimized to improve clinical outcomes for melanoma patients (169)

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