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Data are from the on-treatment observation period (during treatment with trial product [any dose of trial medication administered within the previous 49 days (that is, any period of temporary treatment interruption with trial product was excluded))

Most people notice a small boost in energy within a few days, but it can take 12 weeks to feel a clear and steady improvement

For the majority of people, I recommend once weekly for 4 weeks

If you are asymptomatic, we will usually suggest oral supplementation before any injection

This will be more comfortable Keep the needle still while injecting to avoid snapping it Further Information For further advice and information about your condition, please choose from the following: NHS Patient Choices website: www.nhs.uk Making Lives Better patient website: www.patient.info Telephone NHS 111 Contact your General Practitioner Contact details The James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW Telephone: 01642 850850 The Friarage, Northallerton, North Yorkshire, DL6 1JG Telephone: 01609 779911 Redcar Primary Care Hospital, West Dyke Road, Redcar, TS10 4NW Telephone: 01642 511000 If you have any medical concerns or need advice please contact 111, for further information regarding this leaflet please contact: [email protected] This email will be monitored 9am until 4pm Monday to Friday

However, our nurse and physicians assistant injectors frequently perform cosmetic BOTOX injections