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However, UPR can also activate downstream apoptotic signaling pathways and promote apoptosis when the damage is persistent and severe or when the extent of the crosstalk network exceeds the resolution capacity of ER loading aberrations (55)

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Parolini M, De Felice B, Ferrario C, Salgueiro-Gonzlez N, Castiglioni S, Finizio A (2020) Benzodiazepines and antipsychotics in Norwegian and Italian wastewater treatment plants: a cross-site study

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14 WHO (NCBI Bookshelf)Guideline on safety-engineered syringes and aseptic technique for IM, ID and SC injections (2016)

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