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Changes in brain insulin metabolism and insulin resistance are associated with several CNS disorders such as Alzheimers disease (AD), depression [71,72,73], autism [74], schizophrenia [75], Huntingtons disease [76], Parkinsons disease (PD) [77], etc
Naeimi et al
Quercetin supplemented hypoxia exposed group exhibited no significant change in aldosterone levels in urine when compared with hypoxia exposed group
Moreover, the accumulation of succinate and subsequent disruptions in cellular redox balance can lead to increased oxidative stress
They all possess the highly conserved HEXXH(X)18E zinc-binding and GAMEN motifs essential for enzyme activities (Luan et al., 2012)
C., Orlowski, J., Furthmayr, H
