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Cardiovascular effects including changes in blood pressure or heart rate have been studied, with most research suggesting minimal cardiovascular impact, though some studies have noted modest blood pressure reductions in hypertensive individuals, which could be therapeutic rather than adverse

In addition the drug is associated with the development of Goodpasture's syndrome with linear glomerular basement membrane deposits

But other drug hunters are looking past amyloid- to different therapeutic targets

Dagdag, O., Haldhar, R., & Kim, H

Most research indicates initial effects may be observed within 2-4 weeks of consistent use, with more significant changes typically occurring after 8-12 weeks

Current evidence suggests protective biological roles, but large clinical trials are still needed to define its therapeutic and nutritional significance