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Pro-inflammatory chemokines (e.g., CCL2, CCL3, CCL7, CXCL8, CXCL10 , and CXCL11 ) and C-C motif chemokine receptor ( CCR ) 7 were significantly upregulated, contributing to immune cell recruitment, antigen presentation, and antitumor responses 38,39,40,41,42,43

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To further verify the 4D-label-free proteomics results, we selected proteins related to oxalate degradation, methane synthesis, and antioxidant mechanisms for Parallel Reaction Monitoring (PRM) validation of key differential proteins

10.3390/ijms23094605 92 CrileG