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10.1016/j.msec.2018.11.087 37 DuY.LiJ.TangX.LiuY.BianG.ShiJ.et al (2022)

Similar to ME/CFS patients, the TRPM3 dysfunction in natural killer cells also existed in Long Covid patients but not in healthy controls.[ref] A study involving cells from long Covid patients who were taking LDN showed that the LDN restored TRPM3 ion channel function.[ref] Naltrexone metabolism: The rate at which a drug is broken down (metabolized) affects how long it stays in your system

This process takes place in drugs which contain aromatic rings in their structures

Nabavi SF, Thiagarajan R, Rastrelli L, et al
Both NFT and DEM induced a similar increase in total glutathione levels (Fig

Journal of Medicinal Chemistry, 19 (1), 3740
