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In the mammalian immune system, NF-B plays a critical role as the key regulator of the innate and adaptive immune systems 14,15

1.2.3 Supply issues and environmental sustainability According to a recent market analysis report by Mordor Intelligence, global FBS market is valued at $2.35 billion in 2025 and is projected to reach $4.62 billion by 2030, representing a compound annual growth rate of 14.5%, though estimates vary across forecasting firms (Mordor Intelligence, 2025)

These iron-catalyzed oxidants can further enhance inflammation transcription factors induced by protein and autoantibodies, leading to the production of matrix proteins, cytokines/chemokines, and immune cell infiltration

Dalke, K

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