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Sci Transl Med 2(33):2433

doi: 10.1016/0024-3205(86)90540-0

The peripheral changes in fat metabolism are a downstream consequence of reduced energy intake rather than a direct pharmacological target

After 12 weeks, they had less oxidative damage in their bodies

JHEP Rep

It significantly decreased extracellular ROS generation in PMNs, with an IC 50 value of 17.36 M, comparable to aspirin (Ibanez et al., 2023)