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Notably, TZP was additionally correlated with reductions in patients' plasma lipid concentrations, waist circumferences, and fasting insulin levels

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It mimics endogenous GLP-1, enhancing glucose-dependent insulin secretion, decreasing glucagon secretion, and significantly reducing appetite and energy intake, which leads to clinically meaningful weight loss

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doi:10.1007/s00109-016-1488-y Brcic L, Brcic I, Staresinic M, Novinscak T, Sikiric P, Seiwerth S

Irish Journal of Medical Science, 186, 895902
