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( In vitro experiments showed that glabridin significantly inhibits Akt phosphorylation, suggesting it inhibits prostate cancer cell proliferation by regulating the PI3K/Akt pathway

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Our results indicated that L-MS had no effect on cell proliferation with or without hypoxia, but V-9302 influenced cell proliferation, particularly in combination with aspirin (Fig

Reduced mitochondrial function, including decreased respiratory chain efficiency and impaired ATP production, likely contributes to increased ROS levels, oxidative damage, and diminished antioxidant protein synthesis

10.1021/bi015964x Biochemistry 109 ThompsonJ

The reference 126 has been included in the previous sentence.] Direct apoptosis is mediated through the activation of caspases7 and 8, lysosome permeabilization, and upregulation of reactive oxygen species