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FMN and FAD are coenzymes involved in key enzymatic reactions in energy metabolism, biosynthesis, detoxification and electron scavenging pathways

It is noteworthy that the production of ROS in melanocytes can be amplified under pathological circumstances, exemplified by instances of inflammation and cancer 55

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Villanueva-Paz M, Morn L, Lpez-Alcntara N, Freixo C, Andrade RJ, Lucena MI, Cubero FJ (2021) Oxidative stress in drug-induced liver injury (DILI): from mechanisms to biomarkers for use in clinical practice

[DOI] [PMC free article] [PubMed] [Google Scholar] 255.Desideri E., Ciccarone F., Ciriolo M.R

Since traditional risk factors cannot fully explain such increased cardiovascular risk, interest in non-traditional risk factors, such as hyperhomocysteinemia and folic acid and vitamin B12 metabolism impairment, is growing