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mays , root oxalate (Kidd et al., 2001) and citrate (Pieros et al., 2002) exudation are likely involved in Al-tolerance

In contrast to the GSSG-enhanced P

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The human alpha class GST consists of 5 isozymes that are responsible for detoxifying a broad range of xenobiotics, namely, carcinogens, mutagens, chemotherapeutic drugs, steroids, and byproducts of oxidative stress (12)

In vitro and animal studies have found that lipoic acid exhibits immunomodulatory properties through mechanisms that stimulate the production of cyclic AMP (cAMP) (90, 91) a central regulator of innate immune functions and inhibits the migration of immune cells into the brain and spinal cord (92), possibly by decreasing endothelial expression of cell adhesion molecules, inhibiting expression of enzymes like matrix metalloproteinases (MMP), and/or reducing the permeability of the blood-brain barrier (87, 89, 93, 94)

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