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Accordingly, prominent sex differences exist in oxidative stress, as females are proposed to have overall lower levels of ROS-induced damage, reduced mitochondrial DNA damage, and higher antioxidant enzyme levels, thus being less vulnerable to oxidative insults than males (246, 249, 256)

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Copper peptides GHK-Cu , Haloxyl, niacinamide , and Eyeliss demonstrate clinical evidence with 0.5-1% concentrations proving effective for delicate eye area