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Use sterile handling, avoid vigorous shaking and repeated freeze-thaw cycles, and do not use the material if the seal is damaged or if persistent particles, unexpected cloudiness, or discoloration is present after dissolution

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Each specimen was scored using a scale ranging from 0 to 3 (0: none, 1: mild, 2: moderate, and 3: severe) for each criterion, and a final histology score was determined (0: none, 1: mild, 2: moderate, and 3: severe)

Thus, various intestinal lesions models cured, even when complicated with relapse